The control and management of MRIWA is vested in a Board of seven directors, who are appointed by the Minister. The Minister appoints one director as Chair and one as Deputy Chair.

The Minister does not have day-to-day control over Board decisions, but the Board is ultimately subject to Ministerial directions.

The CEO administers the day‑to‑day operations of the Institute, subject to the control of the Board.

The Advisory Committee of seven members and subject specialist advisory committees provide advice to the Board on various matters, especially on the merit of Applications for research grants. The members of all advisory committees are appointed by the Board.